Semax

Product Overview

Semax is a synthetic heptapeptide amide consisting of seven amino acid residues: Methionine, Glutamic Acid, Histidine, Phenylalanine, Proline, Glycine, and Proline. The peptide features an N-terminal acetylation and a C-terminal amidation, modifications commonly employed to enhance stability in research settings.

Technical Specifications

Structural Context

Semax is a synthetically produced heptapeptide that corresponds to a fragment of a larger endogenous regulatory peptide. The sequence incorporates both polar (Methionine, Glutamic Acid, Histidine) and non-polar (Phenylalanine, Proline, Glycine) residues, with a repeating proline motif at positions 5 and 7. The presence of multiple proline residues introduces conformational constraint to the backbone, resulting in a defined structural profile for analytical investigations. The N-terminal acetylation and C-terminal amidation provide distinct endpoints for analytical method development, chromatographic reference studies, and stability assessments in controlled laboratory environments.

Handling and Storage

The peptide is supplied in lyophilized (freeze-dried) powder form in a 10 mg vial. For optimal stability, store lyophilized material at or below -20°C. Protect from repeated freeze-thaw cycles, moisture, and prolonged exposure to light.