Product Overview
CJC-1295 is a synthetic 29-amino acid amide peptide. The sequence incorporates multiple amino acid residues and features a C-terminal amidation, a modification commonly employed to enhance stability in research settings. The peptide includes strategic amino acid substitutions relative to the native regulatory peptide fragment, including D-Alanine at position 2 and Leucine at position 27.
Technical Specifications
| Sequence (1-Letter) | H-Y-D-Ala-D-A-I-F-T-Q-S-Y-R-K-V-L-A-Q-L-S-A-R-K-L-L-Q-D-I-L-S-R-NH₂ |
|---|---|
| Sequence (3-Letter) | H-Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH₂ |
| CAS Number | 863288-34-0 |
| Molecular Formula | C₁₅₂H₂₅₂N₄₄O₄₂ |
| Molecular Weight | ~3367.8 g/mol |
| Purity (HPLC) | ≥98% |
| Physical Form | Lyophilized powder |
| Vial Content | 10 mg |
Structural Context
CJC-1295 is a synthetic 29-amino acid amide peptide that incorporates strategic amino acid substitutions relative to the native 44-residue hypothalamic regulatory peptide fragment. The introduction of a D-Ala residue at position 2 and a Leu residue at position 27 provides a distinct conformational and stability profile compared to the standard amino acid configuration. The presence of multiple charged residues (Arginine, Lysine, Aspartic Acid) alongside hydrophobic residues (Valine, Leucine, Isoleucine, Phenylalanine) creates an amphipathic molecular architecture suitable for analytical method development, chromatographic reference studies, and peptide solubility assessments in controlled laboratory environments.
Handling and Storage
The peptide is supplied in lyophilized (freeze-dried) powder form. For optimal stability, storage at or below -20°C is recommended. Protect from repeated freeze-thaw cycles and prolonged exposure to light and moisture.
Research Applications
This product is manufactured and supplied as a chemical reference standard for in-vitro laboratory research applications including analytical method development, chromatographic reference studies, stability assessments, and peptide solubility testing in controlled laboratory environments.






