Glutathione

Product Overview

Glutathione, also known as Reduced L-Glutathione or Gamma-L-Glutamyl-L-cysteinylglycine, is a synthetic tripeptide consisting of three amino acid residues: Glutamic Acid, Cysteine, and Glycine. The peptide features a unique gamma-peptide bond between the gamma-carboxyl group of the glutamate side chain and the amino group of cysteine, rather than a standard alpha-peptide bond. The molecule contains a free thiol (sulfhydryl) group.

Technical Specifications

Structural Context

Glutathione is a tripeptide characterized by an atypical gamma-peptide linkage connecting the gamma-carboxyl group of Glutamic Acid to the amino group of Cysteine. This structural arrangement distinguishes it from standard alpha-peptide bonds. The presence of a free thiol group on the cysteine residue provides a redox-active moiety suitable for oxidation-reduction titration studies. The molecule also contains primary amine groups and carboxylic acid groups, contributing to its high aqueous solubility. This defined molecular architecture makes the compound suitable for analytical method development, chromatographic reference studies, spectrophotometric quantification, and stability profiling under varying pH and temperature conditions in controlled laboratory environments.

Handling and Storage

The product is supplied in lyophilized powder form. For optimal stability, store lyophilized material at or below -20°C. Protect from light, moisture, and exposure to oxidizing conditions. Avoid repeated freeze-thaw cycles.